返回首页   中文版ENGLISH

学科介绍及招生公告

来源: hao pp  时间: 2013-10-02     [ ] [ 打印 ] [ 关闭 ] [ 收藏 ]

学科简介:

山东大学齐鲁医院急诊医学专业,2012年被评为卫生部国家临床重点专科,同步建设山东大学急危重症研究所。主要研究方向为急性冠脉综合征、心肺脑复苏、多脏器功能衰竭、急性中毒等。近年来主要开展了急性冠脉综合征和心肺脑复苏的基础和临床研究、动脉粥样硬化研究、基因多态性与心血管疾病相关性研究等。专业特长为急性胸痛的诊断和鉴别诊断、心血管疾病诊治(尤其是心血管介入诊疗)、心肺脑复苏、多脏器功能衰竭、急性中毒等。

学科带头人:

陈玉国教授目前担任山东大学齐鲁医院副院长、急诊科主任、急性胸痛中心主任,山东大学齐鲁医院基层学术委员会委员,兼任中华医学会急诊医学分会常委、急性心血管病学组组长、中国医师协会心血管内科医师分会委员、教育部科技成果奖评审专家、山东省泰山学者特聘教授、山东省医学领军人才 山东省“1020工程杰出学科带头人、山东省医学会急诊医学分会主任委员、山东省急诊医学质控中心主委、山东省预防医学会中毒与临床急病专业委员会副主委、山东省医学会介入心血管分会委员、山东省科技计划与科技成果评审专家、山东省政府应急管理专家组成员,华东地区危重病急救医学专业委员会副主委等职务。 10年发表论著100余篇,SCI收录20余篇,主编和参编著作8部(人民卫生出版社7部)。担任《中华急诊医学杂志》等6种核心和统计源期刊编委或副主编、《American Journal of Cardiology》、《Cardiovascular Pathology》、《中国药理学报(英文版)》、《中华高血压杂志》、《山东大学学报(医学版)》等的审稿专家。参加了全国多部急诊医学统编教材的编写。 获部省级科技进步奖6次、国家及部省级课题9项,目前可支配科研经费200余万。多次主办省级和国家级继续医学教育项目,扩大了山东省急诊医学在全国的影响。2005年开始每年一届全国性大型急诊医学学术会议齐鲁心肺脑复苏及胸痛论坛,论坛的成功召开进一步提升了山东省急诊医学在全国的学术地位。

发表论文:

代表性论文(通讯作者或第一作者所在单位为齐鲁医院急诊科;影响因子3以上;截至2013-9-22):

1. Hao PP, Shang R, Liu YP, Hou GH, Zhang MX, Zhang C, Chen YG*, Zhang Y. Cardiogenic shock from acute ST-segment elevation myocardial infarction induced by severe multivessel coronary vasospasm. Eur Heart J 2013 Sep 6. [Epub ahead of print] (*通讯作者; IF: 14.097)

2. Li CB, Bi YW, Sun WY, Li RJ, Li GS, You BA, Chen WQ, Li DQ, Chen YG*, Zhang Y. Images in cardiology. Aberrant origin of circumflex coronary artery from left subclavian artery. J Am Coll Cardiol 2011;57(1):e1.( *通讯作者; IF: 14.086)

3. Wei S, Wang H, Zhang G, Lu Y, An X, Ren S, Wang Y, Chen Y, White JG, Zhang C, Simon DI, Wu C, Li Z, Huo Y*. Platelet IκB kinase-β deficiency increases mouse arterial neointima formation via delayed glycoprotein Ibα shedding. Arterioscler Thromb Vasc Biol 2013;33(2):241-8. (*通讯作者; IF: 6.368)

4. Wang XP, Chen YG, Qin WD, Zhang W, Wei SJ, Wang J, Liu FQ, Gong L, An FS, Zhang Y, Chen ZY, Zhang MX*. Arginase I attenuates inflammatory cytokine secretion induced by lipopolysaccharide in vascular smooth muscle cells. Arterioscler Thromb Vasc Biol 2011;31(8):1853-60. (*通讯作者;IF: 6.368)

5. Hao PP, Zhang MX, Li RJ, Yang JM, Wang JL, Chen YG*, Zhang Y. Clopidogrel 150 mg/day versus 75 mg/day in patients undergoing percutaneous coronary intervention: a meta-analysis. J Thromb Haemost 2011;9(4):627-37. (*通讯作者;IF: 6.081)

6. Tang M, Zhong M, Shang Y, Lin H, Deng J, Jiang H, Lu H, Zhang Y, Zhang W*. Differential regulation of collagen types I and III expression in cardiac fibroblasts by AGEs through TRB3/MAPK signaling pathway. Cell Mol Life Sci 2008;65(18):2924-32. ( *通讯作者; IF: 5.615)

7. Wei SJ, Xing JH, Wang BL, Xue L, Wang JL, Li R, Qin WD, Wang J, Wang XP, Zhang MX, Chen YG*. Poly(ADP-ribose) polymerase inhibition prevents reactive oxygen species induced inhibition of aldehyde dehydrogenase2 activity. Biochim Biophys Acta 2013;1833(3):479-86. (*通讯作者; IF: 5.538)

8. Xu F, Chen YG*, Li JF, Li GS, Ji QS, Lv RJ, Liu TT, Sun Y, Li RJ, Zhang W, Zhang Y. Facilitated PCI in younger Chinese patients with AMI. Int J Cardiol 2007;121(1):78-80. (*通讯作者; IF: 5.509)

9. Hao PP, Liu YP, Hou GH, Zhang MX, Chen YG, Zhang Y, Zhang C*. Usefulness of angiotensin-(1-7) to predict myocardial salvage after percutaneous coronary intervention in patients with acute myocardial infarction. Int J Cardiol 2013;168(1):614-6. (*通讯作者; IF: 5.509)

10. Wang J, Wang H, Hao P, Xue L, Wei S, Zhang Y, Chen Y*. Inhibition of aldehyde dehydrogenase 2 by oxidative stress is associated with cardiac dysfunction in diabetic rats. Mol Med 2011;17(3-4):172-9. (*通讯作者;IF: 4.469)

11. Liu L, Ding WY, Zhao J, Wang ZH, Zhong M, Zhang W, Chen YG, Zhang Y, Li L, Tang MX*. Activin receptor-like kinase 7 mediates high glucose-induced H9c2 cardiomyoblast apoptosis through activation of Smad2/3. Int J Biochem Cell Biol 2013;45(9):2027-35. (*通讯作者;IF: 4.152)

12. Xu F, Chen YG*, Xue L, Li RJ, Zhang H, Bian Y, Zhang C, Lv RJ, Feng JB, Zhang Y. Role of aldehyde dehydrogenase 2 Glu504lys polymorphism in acute coronary syndrome.Role of aldehyde dehydrogenase 2 Glu504lys polymorphism in acute coronary syndrome. J Cell Mol Med 2011;15(9):1955-62. (*通讯作者;IF: 4.125)

13. Li CB, Li XX, Chen YG, Zhang C, Zhang MX, Zhao XQ, Hao MX, Hou XY, Gong ML, Zhao YX, Bu PL, Zhang Y*. Effects and mechanisms of PPARalpha activator fenofibrate on myocardial remodelling in hypertension. J Cell Mol Med 2009;13(11-12):4444-52. (*通讯作者;IF: 4.125)

14. Wang J, Perrard XD, Perrard JL, Mukherjee A, Rosales C, Chen Y, Smith CW, Pownall HJ, Ballantyne CM, Wu H*. ApoE and the role of very low density lipoproteins in adipose tissue inflammation. Atherosclerosis 2012;223(2):342-9. (*通讯作者;IF: 3.794)

15. Hao PP, Xue L, Wang XL, Chen YG*, Wang JL, Ji WQ, Xu F, Wei SJ, Zhang Y. Association between aldehyde dehydrogenase 2 genetic polymorphism and serum lipids or lipoproteins: a meta-analysis of seven East Asian populations. Atherosclerosis 2010;212(1):213-6. (*通讯作者;IF: 3.794)

16. Li CB, Li XX, Chen YG, Gao HQ, Bu PL, Zhang Y, Ji XP*. Huang-lian-jie-du-tang protects rats from cardiac damages induced by metabolic disorder by improving inflammation-mediated insulin resistance. PLoS One 2013;8(6):e67530. (*通讯作者;IF: 3.730)

17. Hao PP, Chen YG, Liu YP, Zhang MX, Yang JM, Gao F, Zhang Y, Zhang C*. Association of plasma angiotensin-(1-7) level and left ventricular function in patients with type 2 diabetes mellitus. PLoS One 2013;8(5):e62788. (*通讯作者;IF: 3.730)

18. Wang JL, Wang HG, Gao HQ, Zhai GX, Chang P, Chen YG*. Endothelial nitric oxide synthase polymorphisms and erectile dysfunction: a meta-analysis. J Sex Med 2010;7(12):3889-98. (通讯作者;IF: 3.513)

19. Xue L, Xu F, Meng L, Wei S, Wang J, Hao P, Bian Y, Zhang Y, Chen Y*. Acetylation-dependent regulation of mitochondrial ALDH2 activation by SIRT3 mediates acute ethanol-induced eNOS activation. FEBS Letters 2012;586(2):137-42. (*通讯作者;IF: 3.582)

20. Liu YP, Hao PP, Zhang MX, Zhang C, Gao F, Zhang Y, Chen YG*. Association of genetic variants in CYP2C19 and adverse clinical outcomes after treatment with clopidogrel: an updated meta-analysis. Thromb Res 2011;128(6):593-4. (*通讯作者;IF: 3.133)

科研项目:

陈玉国ALDH2在高血糖影响缺血性心肌损伤中的作用及其机制,国家自然科学基金面上项目(81170136),60万元,2012-2015.

蒋凡、张梅、张鹏飞、陈玉国,等,心脑血管易损斑块的高分辨成像识别与风险评估预警体系重大问题的基础研究,易损斑块标记物的高灵敏单分子检测和多模成像的分子靶向研究,973项目分课题(2010CB732605),450万元,2010-2014.

年度招生计划:

可招收急诊医学专业的博士和硕士研究生,从事急性冠脉综合征和心肺脑复苏的基础与临床研究。所培养研究生适合工作领域:急诊医学、ICU、内科学专业等。2014年拟招收硕士生、博士研究生各2-3名。

本篇文章共有  共1页  1 

  • 打印本页
  • 关闭本窗口